Drug-Induced Prolongation of the QT Interval
In the past decade, the single most common cause of the withdrawal or restriction of the use of drugs that have already been marketed has been the prolongation of the QT interval associated with polymorphic ventricular tachycardia, or torsade de pointes (Figure 1), which can be fatal.1 Nine structurally unrelated drugs that were marketed in [...]
Tags: amiodarone, and many antidepressants and antiretroviral agents, Cardiac arrhythmias, clarithromycin, erythromycin, itraconazole, ketoconazole, long QT syndrome, quinidine