Posts Tagged ‘Diabetes and Intercurrent Illness’

Hyperosmolar Hyperglycaemic Non-Ketotic Coma (HONK)

his extreme metabolic derangement occurs through a combination of intercurrent illness, dehydration and an inability to take normal diabetic therapy due to the effect of illness. It is a potentially life-threatening emergency. HONK is characterised by severe hyperglycaemia with marked serum hyperosmolarity, without evidence of significant ketosis. Hyperglycaemia causes an osmotic diuresis with hyperosmolarity leading [...]

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