Posts Tagged ‘multidrug resistant’

Safety and efficacy of polymyxin B in multidrug resistant gram-negative severe sepsis and septic shock

Background and Aims: The emergence of multidrug resistant strains of Gram-negative bacteria, especially the lactose nonfermenters like Pseudomonas and Acinetobacter, in the intensive care units have prompted renewed worldwide interest in the polymyxins. However, perceived nephrotoxicity has been a major vexation limiting their early and regular use in severe sepsis. This study was conducted to [...]

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